Management of Acute Intermediate-risk Pulmonary Embolism: Where Do we Stand in the Era of Upcoming Randomized Controlled Trials?

The role of catheter-directed therapy, in the form of pharmacologic, mechanical, or combination therapy, remains unclear in the treatment of acute pulmonary embolism. Multiple prospective randomized controlled clinical trials are ongoing in an attempt to answer this critical clinical question. This brief manuscript describes the current randomized controlled trials for this disease process.