Immediate or Deferred Nonculprit-Lesion PCI in Myocardial Infarction
Among patients with STEMI who have undergone successful primary PCI, immediate iFR-guided PCI was not superior to deferred cardiac stress MRI-guided PCI of nonculprit coronary-artery lesions with respect to death from any cause, recurrent myocardial infarction, or hospitalization for heart failure at 3 years. (Funded by Philips Volcano and others; iMODERN ClinicalTrials.gov number, NCT03298659.).
Authors
- Rasha Al‐Lamee (ORCID: https://orcid.org/0000-0003-3752-5532)
- Jan J. Piek (ORCID: https://orcid.org/0000-0001-8666-7129)
- Casper W.H. Beijnink (ORCID: https://orcid.org/0000-0003-1777-9586)
- Matjaž Bunc (ORCID: https://orcid.org/0000-0001-7269-8944)
- Michael Mæng (ORCID: https://orcid.org/0000-0002-4310-6433)
- Colette Saraber
- Abdelilah el Barzouhi
- Lars Jakobsen (ORCID: https://orcid.org/0000-0002-2522-9253)
- Juan F. Iglesias (ORCID: https://orcid.org/0000-0002-1669-6036)
- Lieuwe H. Piers
- Stijn L. Brinckman
- Lennaert Kleijn (ORCID: https://orcid.org/0000-0002-4507-7314)
- Lorenzo Monti (ORCID: https://orcid.org/0000-0001-6656-3568)
- Bahram Yosofi
- Robert‐Jan van Geuns (ORCID: https://orcid.org/0000-0003-2943-5932)
- Gabija Pundziūtė (ORCID: https://orcid.org/0000-0002-7558-7331)
- Troels Thim (ORCID: https://orcid.org/0000-0002-1014-5559)
- Dirk J. van der Heijden (ORCID: https://orcid.org/0000-0002-9904-9212)
- Martijn Meuwissen (ORCID: https://orcid.org/0000-0002-5421-5205)
- Sérgio Bravo Baptista (ORCID: https://orcid.org/0000-0002-4546-5261)
- Niels van Royen (ORCID: https://orcid.org/0000-0001-6136-8640)
- Pairoj Chattranukulchai (ORCID: https://orcid.org/0000-0001-6153-8398)
- Johannes Rigger
- Sophie Degrauwe
- Saman Rasoul (ORCID: https://orcid.org/0000-0001-9662-6136)
- Daniel A. Jones (ORCID: https://orcid.org/0000-0003-1441-0417)
- G. Belli (ORCID: https://orcid.org/0000-0001-7312-8548)
- Tomaž Podlesnikar (ORCID: https://orcid.org/0000-0001-6863-9546)
- Johannes B. van Rees
- Robin Nijveldt (ORCID: https://orcid.org/0000-0003-1530-6363)
- Steffen Erhard Petersen (ORCID: https://orcid.org/0000-0003-4622-5160)
- Marcel A.M. Beijk (ORCID: https://orcid.org/0000-0002-7984-3021)
- Igor Klem (ORCID: https://orcid.org/0000-0001-7113-9470)
- José F. Rodríguez‐Palomares (ORCID: https://orcid.org/0000-0002-7229-9780)
- Christian Alcaraz Frederiksen (ORCID: https://orcid.org/0000-0001-6583-2885)
- Javier Escaned (ORCID: https://orcid.org/0000-0003-4932-0112)
- Mustafa İlhan (ORCID: https://orcid.org/0000-0003-1367-6328)
- Arnoud W.J. van ‘t Hof (ORCID: https://orcid.org/0000-0002-2344-7564)
- Henry Seligman (ORCID: https://orcid.org/0000-0002-4244-860X)
- Erik Lipšic (ORCID: https://orcid.org/0000-0002-7407-3064)
- Jan G.P. Tijssen (ORCID: https://orcid.org/0000-0003-1707-2628)
- Bruno Pereira (ORCID: https://orcid.org/0000-0002-8191-6613)
- Luís Raposo (ORCID: https://orcid.org/0000-0003-1001-6017)
- Juan Sanchis
- Justin E. Davies
- René J. van der Schaaf
- Graham Cole
Institutions
- Universitat Autònoma de Barcelona (ES)
- St Bartholomew's Hospital (GB)
- University Medical Center Groningen (NL)
- University of Lisbon (PT)
- Radboud University Nijmegen (NL)
- Universitat de València (ES)
- Queen Mary University of London (GB)
- University of Groningen (NL)
- Aarhus University (DK)
- Barts Health NHS Trust (GB)
- Kantonsspital St. Gallen (CH)
- Princess Grace Hospital Centre (MC)
- Ljubljana University Medical Centre (SI)
- Instituto de Salud Carlos III (ES)
- King Chulalongkorn Memorial Hospital (TH)
- Aarhus University Hospital (DK)
- Radboud University Medical Center (NL)
- Hospital Clínico San Carlos (ES)
- Maastricht University (NL)
- Istituti Clinici Scientifici Maugeri (IT)
- Hospital Clínico Universitario de Valencia (ES)
- Medisch Centrum Haaglanden (NL)
- Hospital Prof. Dr. Fernando Fonseca (PT)
- Lung Institute (US)
- Ospedale San Carlo (IT)
- Vall d'Hebron Institut de Recerca (ES)
- Amphia Ziekenhuis (NL)
- Amsterdam Neuroscience (NL)
- Treant Zorggroep (NL)
- Centro de Investigación Biomédica en Red (ES)
- Hospital de Santa Cruz (PT)
- Centro Hospitalar de Lisboa Ocidental (PT)
- Duke Medical Center (US)
- Vall d'Hebron Hospital Universitari (ES)
- University Clinical Centre Maribor (SI)
- Zuyderland Medisch Centrum (NL)
- Laboratoire National de Santé (LU)
- Isala (NL)
- Tergooi (NL)
- William Harvey Research Institute (GB)
- Amsterdam University Medical Centers (NL)
- Rijnstate Hospital (NL)
- INCLIVA Health Research Institute (ES)
- Instituto de Investigación de Enfermedades Raras (ES)
- Imperial College London (GB)
- Geneva College (US)
- University of Amsterdam (NL)
Publication Details
- Journal
- New England Journal of Medicine
- Published
- 2025-10-28
- DOI
- https://doi.org/10.1056/nejmoa2512918
- Citations
- 3
- Primary Topic
- Cardiac Imaging and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 4.08