Trajectories of Clozapine Concentrations in Women Across Menopausal Age
Sex-specific longitudinal trajectories of clozapine concentrations showed declines in 60% of women aged 40-60, while most men remained stable. As decreasing blood levels could increase relapse vulnerability, monitoring clinical efficacy and side effects is warranted during menopause.
Authors
- Daan J. Touw (ORCID: https://orcid.org/0000-0002-1429-4789)
- Iris E. Sommer (ORCID: https://orcid.org/0000-0001-5597-3262)
- Shiral S. Gangadin (ORCID: https://orcid.org/0000-0002-0084-8226)
- Georgios Schoretsanitis (ORCID: https://orcid.org/0000-0002-3851-4117)
- Franciska de Beer (ORCID: https://orcid.org/0000-0002-0740-0969)
- Iris M. H. Hamers (ORCID: https://orcid.org/0009-0007-0296-3969)
- Michalina Prycka
Institutions
- University Medical Center Groningen (NL)
- University of Groningen (NL)
- University of Zurich (CH)
- University Hospital of Zurich (CH)
- Zucker Hillside Hospital (US)
Publication Details
- Journal
- Schizophrenia Bulletin
- Published
- 2025-09-30
- DOI
- https://doi.org/10.1093/schbul/sbaf186
- Citations
- 2
- Primary Topic
- Schizophrenia research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.94