Stratified treatment of myocardial infarction with non-obstructive coronary arteries: the PROMISE trial
In this first randomized trial of treatment strategies in MINOCA, a stratified treatment, based on comprehensive diagnostic assessment and aetiology-guided therapy, led to a significant improvement in angina-related health status. While the study findings provide the first evidence supporting individualized management in this heterogeneous and often under-recognized patient population, these results require confirmation in a larger prospective study with longer follow-up.
Authors
- Tommaso Sanna (ORCID: https://orcid.org/0000-0002-5760-6885)
- Federico De Marco (ORCID: https://orcid.org/0000-0003-3554-6938)
- Claudia Lucci (ORCID: https://orcid.org/0000-0002-7188-737X)
- Giancarlo Marenzi (ORCID: https://orcid.org/0000-0003-4410-4461)
- Nicola Cosentino (ORCID: https://orcid.org/0000-0002-8628-3106)
- Giampaolo Niccoli (ORCID: https://orcid.org/0000-0002-3187-6262)
- Francesco Bedogni (ORCID: https://orcid.org/0000-0002-6651-0041)
- Filippo Crea (ORCID: https://orcid.org/0000-0002-9482-411X)
- Simone Biscaglia (ORCID: https://orcid.org/0000-0001-6074-2370)
- Andrea Caffè (ORCID: https://orcid.org/0000-0001-5264-1043)
- Riccardo Gorla (ORCID: https://orcid.org/0000-0003-4682-5289)
- Luca Testa (ORCID: https://orcid.org/0000-0003-4687-3686)
- Antonio Maria Leone (ORCID: https://orcid.org/0000-0002-1276-9883)
- Giovanna Liuzzo (ORCID: https://orcid.org/0000-0002-5714-0907)
- Francesco Bedogni (ORCID: https://orcid.org/0000-0002-4975-6605)
- Marta Resta
- Giulia La Vecchia (ORCID: https://orcid.org/0000-0002-4324-6348)
- Gianluca Calogero Campo (ORCID: https://orcid.org/0000-0002-5150-188X)
- Filippo Luca Gurgoglione (ORCID: https://orcid.org/0000-0001-7539-5463)
- Carlo Trani (ORCID: https://orcid.org/0000-0001-9777-013X)
- Filippo Crea (ORCID: https://orcid.org/0000-0001-9404-8846)
- Rocco Antonio Montone (ORCID: https://orcid.org/0000-0002-6439-1018)
- Riccardo Rinaldi (ORCID: https://orcid.org/0000-0003-0559-2626)
- Alice Bonanni (ORCID: https://orcid.org/0000-0001-8382-255X)
- Francesco Burzotta (ORCID: https://orcid.org/0000-0002-6569-9401)
- Federico De Marco
- Vincenzo Scarica
Institutions
- Università Cattolica del Sacro Cuore (IT)
- University of Parma (IT)
- Agostino Gemelli University Polyclinic (IT)
- Centro Cardiologico Monzino (IT)
- IRCCS Policlinico San Donato (IT)
- Azienda Unità Sanitaria Locale di Ferrara (IT)
- University Hospitals Parma Medical Center (US)
- Arcispedale Sant'Anna (IT)
- University of the Sacred Heart (JP)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- European Heart Journal
- Published
- 2025-10-26
- DOI
- https://doi.org/10.1093/eurheartj/ehaf917
- Citations
- 9
- Primary Topic
- Cardiac Imaging and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 12.24