Acute and transient change in brain water content induced by a single electroconvulsive therapy session
A single ECT-induced seizure induces a transient increase in extracellular water content without evidence of cytotoxic edema indicative of cellular injury. Our findings suggest that ECT-related brain water shifts are reversible and unlikely to reflect permanent damage to brain tissue.
Authors
- Akihiro Takamiya (ORCID: https://orcid.org/0000-0003-2985-6673)
- Louise Emsell (ORCID: https://orcid.org/0000-0003-0011-4158)
- Vera Jane Erchinger (ORCID: https://orcid.org/0000-0002-3799-6388)
- Ute Keßler (ORCID: https://orcid.org/0000-0002-2002-5518)
- Ivan I. Maximov (ORCID: https://orcid.org/0000-0001-6319-6774)
- Max Korbmacher (ORCID: https://orcid.org/0000-0002-8113-2560)
- Leif Oltedal (ORCID: https://orcid.org/0000-0003-3316-7950)
- Ketil J. Øedegaard (ORCID: https://orcid.org/0000-0002-3362-4317)
- Frank Riemer (ORCID: https://orcid.org/0000-0002-3805-5221)
- Hauke Bartsch (ORCID: https://orcid.org/0000-0003-1486-4128)
- Anders M. Dale (ORCID: https://orcid.org/0000-0002-6126-2966)
- Olga Therese Ousdal (ORCID: https://orcid.org/0000-0002-0728-3141)
Institutions
- Allen Institute for Brain Science (US)
- Haukeland University Hospital (NO)
- University of California San Diego (US)
- Western Norway University of Applied Sciences (NO)
- VIB-KU Leuven Center for Brain & Disease Research (BE)
- University of Bergen (NO)
- KU Leuven (BE)
Publication Details
- Journal
- Brain stimulation
- Published
- 2025-10-28
- DOI
- https://doi.org/10.1016/j.brs.2025.10.021
- Citations
- 1
- Primary Topic
- Electroconvulsive Therapy Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.47