Electrophysical and Biological Properties of Lithium-Doped Hydroxyapatite In Vitro
The effect of the concentration of lithium introduced into hydroxyapatites is investigated over the broad range of 1 to 20 mol %. It is shown that raising the content of Li+ ions results in a corresponding increase in the relative permittivity. The incorporation of lithium does not induce acute cytotoxicity. Rather, it enhances the proliferation of the MG-63 cell line during in vitro experiments, with observed positive dynamics over periods of up to 7 days.
Authors
- А. В. Леонов
- M. A. Goldberg
- V. S. Komlev (ORCID: https://orcid.org/0000-0003-2068-7746)
- О. С. Антонова (ORCID: https://orcid.org/0000-0001-9651-4580)
- С. В. Смирнов (ORCID: https://orcid.org/0000-0002-7993-162X)
- С. А. Ахмедова
- А. С. Фомин (ORCID: https://orcid.org/0000-0001-7554-3294)
- Н. С. Сергеева (ORCID: https://orcid.org/0000-0001-7406-9973)
- В. А. Кирсанова (ORCID: https://orcid.org/0000-0002-8806-9234)
- Т. О. Оболкина (ORCID: https://orcid.org/0000-0001-9826-8694)
- Marat Gafurov (ORCID: https://orcid.org/0000-0002-2179-2823)
- И. К. Свиридова (ORCID: https://orcid.org/0000-0003-0848-1542)
- С. М. Баринов
- I. V. Lounev
Institutions
- Lomonosov Moscow State University (RU)
- Kazan Federal University (RU)
- Ministry of Health (ES)
- Baikov Institute of Metallurgy and Materials Science (RU)
- Institute of Physics (RU)
- P.A. Hertzen Moscow Oncology Research Institute (RU)
Publication Details
- Journal
- Bulletin of the Russian Academy of Sciences Physics
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1134/s1062873825713030
- Primary Topic
- Bone Tissue Engineering Materials
- Type
- article
- Field-Weighted Citation Impact
- 0.00