Development and application of a method for quantitative monitoring of Isepamicin concentration in human plasma based on liquid chromatography-mass spectrometry
The UHPLC-MS/MS method is a robust tool for the determination of ISP, and the validated method has been successfully applied to monitor plasma drug concentrations in patients using ISP.
Authors
- Yanru Liu (ORCID: https://orcid.org/0000-0002-1367-8481)
- Lili Cui (ORCID: https://orcid.org/0000-0002-0668-2837)
- Deduo Xu (ORCID: https://orcid.org/0000-0002-2644-9303)
- Zhipeng Wang (ORCID: https://orcid.org/0000-0002-7964-9288)
- Shouhong Gao
- Tao Xia (ORCID: https://orcid.org/0000-0002-3940-688X)
- Jingxue Liu (ORCID: https://orcid.org/0000-0002-6882-6699)
- Yi Shan
Institutions
- Second Military Medical University (CN)
- Fudan University (CN)
- Shanghai Changzheng Hospital (CN)
- Pudong Medical Center (CN)
Publication Details
- Journal
- Journal of Pharmacological Sciences
- Published
- 2025-10-28
- DOI
- https://doi.org/10.1016/j.jphs.2025.10.003
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 0.00