Upstaging of Patients Diagnosed with Favorable Intermediate-Risk Prostate Cancer—Is Active Surveillance Really a Suitable Approach for All These Patients?

Nearly 1/3 of FIR PCa patients were upstaged to high-risk PCa at RP. Based on these findings, AS in clinical practice should only be considered after thorough patient counseling and performed using a stringent follow-up and staging regimen to minimize the risk of further disease progression. A key limitation is the lack of the percentage of Gleason pattern 4.

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Publication Details

Journal
Cancers
Published
2025-10-27
DOI
https://doi.org/10.3390/cancers17213444
Primary Topic
Prostate Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Upstaging of Patients Diagnosed with Favorable Intermediate-Risk Prostate Cancer—Is Active Surveillance Really a Suitable Approach for All These Patients?

Miriam Dellino, Florian Roghmann, Sebastian Berg, Joachim Noldus et al.
Cancers
Prostate Cancer Diagnosis and Treatment
article

Upstaging of Patients Diagnosed with Favorable Intermediate-Risk Prostate Cancer—Is Active Surveillance Really a Suitable Approach for All These Patients?

Miriam Dellino, Florian Roghmann, Sebastian Berg, Joachim Noldus, Jan Philipp Radtke, Karl H. Tully, Analena Handke, Rein‐Jüri Palisaar, Christopher Orf, Leon Miguel Garcia-Schürmann
article en

Abstract

Nearly 1/3 of FIR PCa patients were upstaged to high-risk PCa at RP. Based on these findings, AS in clinical practice should only be considered after thorough patient counseling and performed using a stringent follow-up and staging regimen to minimize the risk of further disease progression. A key limitation is the lack of the percentage of Gleason pattern 4.

CancersVol. 17(21)
University Hospitals of the Ruhr-University of Bochum (DE), Universitätsklinik Marien Hospital Herne (DE), Düsseldorf University Hospital (DE), Heinrich Heine University Düsseldorf (DE)
Openalex Percentile: Top 55%
Prostate Cancer Diagnosis and Treatment
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Upstaging of Patients Diagnosed with Favorable Intermediate-Risk Prostate Cancer—Is Active Surveillance Really a Suitable Approach for All These Patients? — Miriam Dellino, Florian Roghmann, et al. · Cancers (2025) | TGRS Research Map | TGRS