Unravelling the Tumourigenesis Mechanisms of Oncocytic Cell Tumours: Discoveries from a Comparative Omics Study
Most of the DEPs were involved in three key cellular pathways: epigenetic regulation, the tumour microenvironment, and protein biogenesis, suggesting that these processes may underlie the distinctive morphology and behaviour of OCTs. These findings highlight the need for continued research into these molecular mechanisms to improve the diagnostic accuracy and develop targeted therapies for patients with OCTs.
Authors
- Carla Oliveira (ORCID: https://orcid.org/0000-0002-2139-0904)
- Luı́sa Pereira (ORCID: https://orcid.org/0000-0002-4271-1527)
- M. Ferreira (ORCID: https://orcid.org/0000-0003-4833-351X)
- Şule Canberk (ORCID: https://orcid.org/0000-0002-3736-1323)
- Paula Soares (ORCID: https://orcid.org/0000-0001-9607-6998)
- Arnaud Da Cruz Paula (ORCID: https://orcid.org/0000-0001-7694-8760)
- Hugo Osório (ORCID: https://orcid.org/0000-0002-6362-8255)
- Valdemar Máximo (ORCID: https://orcid.org/0000-0002-8631-8356)
Institutions
- Universidade do Porto (PT)
- Centre for Health Technology and Services Research (PT)
- i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto (PT)
Publication Details
- Journal
- Pathobiology
- Published
- 2025-10-28
- DOI
- https://doi.org/10.1159/000548985
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00