The COR Lipid Registry: the effectiveness of the strike early and strike strong strategy in patients with high cardiovascular risk
An optimized LLT-strategy for managing a very-high CV risk patient cohort undergoing PCI, starting with a dual LLT-strategy consisting of a high-dose, highly effective statin plus ezetimibe at the index event followed by addition of a third LL-agent (a PCSK9-inhibitor or bempedoic acid) at follow-up after 4-6 weeks if treatment goal was not reached, was highly effective in achieving LDL-C and non-HDL-C goals. Wider adoption of this strategy may help to significantly improve LDL-C-target levels in real-world populations in very-high risk CAD patients presenting with ACS or CCS for coronary revascularisation.
Authors
- Patrick Weltler (ORCID: https://orcid.org/0000-0001-5880-1175)
- Christoph C. Kaufmann (ORCID: https://orcid.org/0000-0002-4710-0522)
- Stephan Dobner (ORCID: https://orcid.org/0000-0003-2220-9799)
- Achim Leo Burger (ORCID: https://orcid.org/0000-0001-9041-3797)
- Edita Pogran (ORCID: https://orcid.org/0000-0002-5409-6816)
- Alexander Geppert (ORCID: https://orcid.org/0009-0005-6654-6764)
- Paul F Harbich
- Kurt Huber (ORCID: https://orcid.org/0000-0003-1695-3378)
Institutions
- Sigmund Freud Privatuniversität Wien (AT)
- National Heart Foundation of Australia (AU)
- Heart Foundation (US)
- Ludwig Boltzmann Institute for Cancer Research (AT)
- Ludwig Boltzmann Institute for Digital Health and Prevention (AT)
- Medical University of Vienna (AT)
Publication Details
- Journal
- European Heart Journal Acute Cardiovascular Care
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1093/ehjacc/zuaf137
- Citations
- 1
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 2.01