Chronic Infections as Catalysts for Melanoma Aggressiveness: Insights into Tumour Microenvironment Modulation
Chronic microbial infections significantly influence melanoma aggressiveness and treatment resistance. AMPs offer a promising, multifunctional therapeutic approach, addressing infection control and tumour microenvironment modulation. Combining AMPs with current immunotherapies may enhance melanoma management. Further research and clinical trials are needed to validate and optimise AMP-based treatments for personalised care.
Authors
- Octávio Luiz Franco (ORCID: https://orcid.org/0000-0001-9546-0525)
- Ana Cristina Jacobowski (ORCID: https://orcid.org/0000-0001-8233-0713)
- Marlon Henrique e Silva Cardoso (ORCID: https://orcid.org/0000-0001-6676-5362)
- Layza Sá Rocha (ORCID: https://orcid.org/0000-0002-5330-5452)
- Maria Lı́gia Rodrigues Macedo (ORCID: https://orcid.org/0000-0001-6969-6307)
- E. F. dos Reis
Institutions
- Universidade Federal de Mato Grosso do Sul (BR)
- Universidade Católica de Brasília (BR)
- Universidade Católica Dom Bosco (BR)
Publication Details
- Journal
- Asian Pacific Journal of Cancer Prevention
- Published
- 2025-10-01
- DOI
- https://doi.org/10.31557/apjcp.2025.26.10.3531
- Primary Topic
- Cancer Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Financiadora de Estudos e Projetos
- Fundação de Apoio ao Desenvolvimento do Ensino, Ciência e Tecnologia do Estado de Mato Grosso do Sul
- Universidade Federal de Mato Grosso do Sul