Oxidative Stress Dynamic among Helicobacter pylori-Positive Patients with Various Stages of Premalignant Histologic Lesions: A Prospective Study in Cameroon
Our findings showed significant higher and progressive serum levels of lipid peroxidation and antioxidant protective factors with progression in precancerous lesions related to H. pylori infection. This suggests a higher free radical formation and oxidative stress, which increases from chronic gastritis to malignancy.
Authors
- Laure Brigitte Kouitcheu Mabeku (ORCID: https://orcid.org/0000-0002-6447-1413)
- Isabelle Timba
- Ghislaine Ngatcha
- Paul Talla (ORCID: https://orcid.org/0000-0003-1325-5021)
- Sartre Michele Tagni
- Carole Marlyse Menzy Moungo‐Ndjole
- Faujo Nintewoue Ghislaine Florice
- Lionel Dannyl Tali Nguefak
Institutions
- Université de Yaoundé I (CM)
- Université de Dschang (CM)
- Catholic University of Central Africa (CM)
- Yaoundé General Hospital (CM)
- Institut Supérieur de Technologie Médicale (CM)
Publication Details
- Journal
- Asian Pacific Journal of Cancer Prevention
- Published
- 2025-10-01
- DOI
- https://doi.org/10.31557/apjcp.2025.26.10.3609
- Primary Topic
- Helicobacter pylori-related gastroenterology studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00