Association of IFNL4 and IFITM3 Genetic Variants with Susceptibility to HCV-Related Liver Cirrhosis and Hepatocellular Carcinoma

Our results indicate that the IFITM3 rs12252 and IFNL4 rs12979860 genetic polymorphisms are linked to the development of cirrhosis and HCC in patients chronically infected with HCV.

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Publication Details

Journal
Asian Pacific Journal of Cancer Prevention
Published
2025-10-01
DOI
https://doi.org/10.31557/apjcp.2025.26.10.3805
Primary Topic
interferon and immune responses
Type
article
Field-Weighted Citation Impact
0.00
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article

Association of IFNL4 and IFITM3 Genetic Variants with Susceptibility to HCV-Related Liver Cirrhosis and Hepatocellular Carcinoma

Enas Osman, Rania M. Abbas, Hany Aly, Ethar Mokhtar Badran et al.
Asian Pacific Journal of Cancer Prevention
interferon and immune responses
article

Association of IFNL4 and IFITM3 Genetic Variants with Susceptibility to HCV-Related Liver Cirrhosis and Hepatocellular Carcinoma

Enas Osman, Rania M. Abbas, Hany Aly, Ethar Mokhtar Badran, Farida Mohamed Khanany, Medhat Madbouly, Marwa Mohamed
article en

Abstract

Our results indicate that the IFITM3 rs12252 and IFNL4 rs12979860 genetic polymorphisms are linked to the development of cirrhosis and HCC in patients chronically infected with HCV.

Asian Pacific Journal of Cancer PreventionVol. 26(10)
Ain Shams University (EG), Theodor Bilharz Research Institute (EG)
Openalex Percentile: Top 68%
interferon and immune responses
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