Causal relationship between chronic inflammatory diseases and uveal melanoma: A bidirectional Mendelian randomization study

This study confirmed through MR analysis that CD was a potential risk factor for UVM. Additionally, CARD9 and TNFSF15 were identified as key genes closely associated with patient prognosis, providing new evidence for the pathogenic mechanisms of UVM. These findings were of significant importance for the prevention and control of UVM risk in patients with chronic inflammation, as well as for the development of personalized treatment strategies.