ANALYSIS OF THE ASSOCIATION OF rs1333049-POLYMORPHIC VARIANTS OF THE ANRIL GENE WITH THE DEVELOPMENT OF CLEAR CELL RENAL CELL CARCINOMA IN UKRAINIAN POPULATION
Conclusions: The rs1333049 polymorphism of the ANRIL gene increases ccRCC risk. GC and CC genotypes raise risk 2.07-fold (P=0.0392), up to 3.1-fold (P=0.040) after adjustments. In males, CC genotype increases risk 2.5-fold (P=0.02) and 3.12-fold (P=0.05) after adjustments. No link to overall survival was found (P=0.4321).
Authors
- Yelizaveta Antonivna Harbuzova (ORCID: https://orcid.org/0000-0003-3366-8800)
- Olha Anatoliivna Obukhova (ORCID: https://orcid.org/0000-0002-2104-8412)
- А. D. Volkogon (ORCID: https://orcid.org/0000-0003-0835-0657)
Institutions
- Sumy State University (UA)
Publication Details
- Journal
- Wiadomości Lekarskie
- Published
- 2025-10-28
- DOI
- https://doi.org/10.36740/wlek/204031
- Citations
- 1
- Primary Topic
- Renal cell carcinoma treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.52