One Size Does Not Fit All: Novel Individualized Use of Dexamethasone in Infantile Epileptic Spasms Syndrome

Dexamethasone is an effective alternative to ACTH and prednisolone in IESS therapy. Our therapy regimen is effective, well tolerated, and flexible. Reflecting its potential as an individualized, patient-tailored approach, we demonstrate that fewer pulses may suffice to achieve a relapse-free remission in carefully selected patient cohorts.