Sodium bicarbonate to the ROSCue: a case report on how sodium bicarbonate successfully resuscitated a patient in cardiac arrest from suspected quetiapine and trazodone overdose

Trazodone, a popular sleep medication, rarely leads to cardiac arrhythmias, and secondary cardiac arrest is exceptionally rare. Nonetheless, both trazodone and quetiapine can cause SCB in toxic doses. Intravenous SB can rapidly overcome medication-induced SCB and narrow a prolonged QRS and/or QTc interval. Although the role of SB in cardiac arrest remains limited, SB in SCB toxicity in TCA overdose <i>and</i> in other drug toxicities can be life-saving. SB should be considered in patients with wide QRS and suspected drug overdose.