Integrative Approach Based on DI‐MS and LC–MS/MS Analysis for Comprehensive Characterization of Flavonoid Glycoside Isomers From <i>Onychopetalum periquino</i> (Annonaceae)

This study demonstrated the efficacy of the proposed strategy in identifying and differentiating flavonoid glycoside isomers in O. periquino leaves. Therefore, this workflow is an effective approach for the comprehensive characterization of flavonoid glycoside isomers in future dereplication works. Additionally, it showed how structural differences, such as the type of linkage and position of sugars, influence their fragmentation patterns.

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Publication Details

Journal
Rapid Communications in Mass Spectrometry
Published
2025-10-28
DOI
https://doi.org/10.1002/rcm.10163
Primary Topic
Traditional and Medicinal Uses of Annonaceae
Type
article
Field-Weighted Citation Impact
0.00

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article

Integrative Approach Based on DI‐MS and LC–MS/MS Analysis for Comprehensive Characterization of Flavonoid Glycoside Isomers From Onychopetalum periquino (Annonaceae)

Francinaldo A. da Silva Filho, Carromberth Carioca Fernandes, Ruan Guilherme de Oliveira França, Afonso Duarte Leão de Souza et al.
Rapid Communications in Mass Spectrometry
Traditional and Medicinal Uses of Annonaceae
article

Integrative Approach Based on DI‐MS and LC–MS/MS Analysis for Comprehensive Characterization of Flavonoid Glycoside Isomers From Onychopetalum periquino (Annonaceae)

Francinaldo A. da Silva Filho, Carromberth Carioca Fernandes, Ruan Guilherme de Oliveira França, Afonso Duarte Leão de Souza, Felipe M. A. da Silva, Héctor H. F. Koolen, Maria Lúcia B. Pinheiro, Bruna Ribeiro de Lima, Brenda R. C. Leocadio, A. Castro
article en

Abstract

This study demonstrated the efficacy of the proposed strategy in identifying and differentiating flavonoid glycoside isomers in O. periquino leaves. Therefore, this workflow is an effective approach for the comprehensive characterization of flavonoid glycoside isomers in future dereplication works. Additionally, it showed how structural differences, such as the type of linkage and position of sugars, influence their fragmentation patterns.

Rapid Communications in Mass SpectrometryVol. 40(2)
Universidade Federal do Acre (BR), Instituto Nacional de Pesquisas da Amazônia (BR), Escola Superior de Ciências da Saúde (BR), Universidade Federal do Amazonas (BR)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Conselho Nacional de Desenvolvimento Científico e Tecnológico, Financiadora de Estudos e Projetos, Fundação de Amparo à Pesquisa do Estado do Amazonas
Openalex Percentile: Top 69%
Traditional and Medicinal Uses of Annonaceae
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