Rutin Suppresses EMT and Induces Mitochondrial Biogenesis <i>via</i> ER Stress-linked AMPK/SIRT1 Signaling in Prostate Cancer Cells
Rutin inhibits prostate cancer progression by suppressing EMT, inducing mitochondrial biogenesis, and acting <i>via</i> ER stress-linked AMPK/SIRT1 signaling. These findings suggest that Rutin may serve as a potential therapeutic candidate for advanced prostate cancer.
Authors
- Yu‐Lin Yang (ORCID: https://orcid.org/0000-0002-0380-4237)
- Wei‐Lun Huang (ORCID: https://orcid.org/0000-0002-5503-9418)
- Sih-Han Chen
- Hsing‐Chia Mai (ORCID: https://orcid.org/0000-0002-1352-6680)
- Chun‐Quan Ou (ORCID: https://orcid.org/0000-0001-6866-7213)
- Richard C. Wu (ORCID: https://orcid.org/0000-0001-9925-9677)
- Pei‐Fang Hsieh
- Victor C. Lin (ORCID: https://orcid.org/0000-0003-0075-7014)
- Chun‐Hsien Wu (ORCID: https://orcid.org/0000-0003-2205-6403)
Institutions
- Chung Hwa University of Medical Technology (TW)
- E-Da Hospital (TW)
- Chest Hospital, Ministry of Health and Welfare (TW)
- National Cheng Kung University Hospital (TW)
- I-Shou University (TW)
Publication Details
- Journal
- Cancer Genomics & Proteomics
- Published
- 2025-10-28
- DOI
- https://doi.org/10.21873/cgp.20550
- Citations
- 1
- Primary Topic
- Metabolism, Diabetes, and Cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.81