Immunoliposome for Ewing Sarcoma

Immunoliposomes covered with anti-CD99 mAbs and loaded with small-molecule niraparib may be developed as an adjuvant therapy for advanced EWS. Projected 100 nm IL should provide vascular permeability and tumor tropism; however, extensive preclinical evaluations will also be required regarding hematopoietic and endothelial damage.

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Publication Details

Journal
Cancer Genomics & Proteomics
Published
2025-10-28
DOI
https://doi.org/10.21873/cgp.20544
Primary Topic
Nanoparticle-Based Drug Delivery
Type
article
Field-Weighted Citation Impact
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article

Immunoliposome for Ewing Sarcoma

DANIEL E. PANOSYAN, WILLIAM S. PANOSYAN, Joseph L. Lasky, DARON S. YACOUBIAN
Cancer Genomics & Proteomics
Nanoparticle-Based Drug Delivery
article

Immunoliposome for Ewing Sarcoma

DANIEL E. PANOSYAN, WILLIAM S. PANOSYAN, Joseph L. Lasky, DARON S. YACOUBIAN
article en

Abstract

Immunoliposomes covered with anti-CD99 mAbs and loaded with small-molecule niraparib may be developed as an adjuvant therapy for advanced EWS. Projected 100 nm IL should provide vascular permeability and tumor tropism; however, extensive preclinical evaluations will also be required regarding hematopoietic and endothelial damage.

Cancer Genomics & ProteomicsVol. 22(6)
University of California, Los Angeles (US), Cure 4 The Kids Foundation (US)
Openalex Percentile: Top 79%
Nanoparticle-Based Drug Delivery
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