Inherited Genetic Risk of Liver Fibrosis in Lean Versus Nonlean Metabolic Dysfunction–Associated Steatotic Liver Disease ( <scp>MASLD</scp> )
The prevalence of significant fibrosis and the effect of GRS were similar in lean and nonlean MASLD, highlighting that lean MASLD patients may have a comparable risk to overweight and obese MASLD.
Authors
- Egbert Madamba (ORCID: https://orcid.org/0000-0002-4065-3538)
- Sadhu Lokanadham
- Daniel Q. Huang (ORCID: https://orcid.org/0000-0002-5165-5061)
- Luis Antonio Díaz (ORCID: https://orcid.org/0000-0002-8540-4930)
- Mísia Joyner de Sousa Dias Monteiro (ORCID: https://orcid.org/0000-0002-2863-4094)
- Adrian Carlos Gadano (ORCID: https://orcid.org/0000-0002-3590-2472)
- Veeral Ajmera (ORCID: https://orcid.org/0000-0001-5626-0942)
- Amit V. Khera (ORCID: https://orcid.org/0000-0001-6535-5839)
- Gil F. Salles (ORCID: https://orcid.org/0000-0001-6318-7077)
- Nathalie Carvalho Leite (ORCID: https://orcid.org/0000-0001-9066-0405)
- Fernando Javier Barreyro (ORCID: https://orcid.org/0000-0002-0410-2982)
- Mário Reis Álvares‐da‐Silva (ORCID: https://orcid.org/0000-0002-5001-246X)
- Francisco Javier Idalsoaga (ORCID: https://orcid.org/0000-0001-5607-0698)
- Mário Guimarães Pessôa (ORCID: https://orcid.org/0000-0002-0942-7348)
- Saaket Agrawal (ORCID: https://orcid.org/0000-0002-2535-4759)
- Juan Pablo Arab (ORCID: https://orcid.org/0000-0002-8561-396X)
- Cláudia Alves Couto (ORCID: https://orcid.org/0000-0002-9776-4757)
- Rohit Seth Loomba (ORCID: https://orcid.org/0000-0002-4845-9991)
- Marco A. Arrese (ORCID: https://orcid.org/0000-0002-0499-4191)
- Seema Singh (ORCID: https://orcid.org/0000-0001-9382-0603)
- Kaleb Tesfai (ORCID: https://orcid.org/0000-0001-5968-2294)
- Claudia Regina Cardoso
- Cristiane Alves Villela‐Nogueira (ORCID: https://orcid.org/0000-0003-1355-2368)
- Sebastián Marciano (ORCID: https://orcid.org/0000-0002-7983-1450)
- Ricki Bettencourt (ORCID: https://orcid.org/0000-0001-6267-1078)
- Cláudia P. Oliveira (ORCID: https://orcid.org/0000-0002-2848-417X)
- Gustavo Ayares (ORCID: https://orcid.org/0000-0002-8651-2255)
- Rafael Theodoro
- Jorge Martínez Morales
- Lisa Richards
Institutions
- Broad Institute (US)
- Western University (CA)
- Brigham and Women's Hospital (US)
- Pontificia Universidad Católica de Chile (CL)
- National University of Misiones (AR)
- Virginia Commonwealth University (US)
- London Health Sciences Centre (CA)
- Hospital Italiano de Buenos Aires (AR)
- University of California San Diego (US)
- Hospital de Clínicas de Porto Alegre (BR)
- Verve Therapeutics (United States) (US)
- Hospital das Clínicas da Universidade Federal de Minas Gerais (BR)
- Hospital Universitário Clementino Fraga Filho (BR)
- Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
Publication Details
- Journal
- Alimentary Pharmacology & Therapeutics
- Published
- 2025-10-28
- DOI
- https://doi.org/10.1111/apt.70433
- Citations
- 5
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 6.77