Dynamic molecular and cellular characteristics of VSX2-positive retinal progenitor cells in human retinal organoids
This study provides valuable insights into the molecular and cellular characteristics of human RPCs, especially their expression profiles of CD biomarkers, laying a foundation for research on retinal development and the clinical translation of hiPSC-derived RPCs.
Authors
- Mengqing Xiang (ORCID: https://orcid.org/0000-0002-9734-7646)
- Xiaoming Yu (ORCID: https://orcid.org/0000-0002-4138-7649)
- Xiufeng Zhong (ORCID: https://orcid.org/0000-0001-8211-261X)
- Dandan Zheng (ORCID: https://orcid.org/0000-0002-2571-5526)
- Bingbing Xie (ORCID: https://orcid.org/0000-0002-8573-442X)
- Yuan Wang (ORCID: https://orcid.org/0000-0002-7981-4829)
- Fuhua Peng (ORCID: https://orcid.org/0000-0002-2005-4802)
- Ping Xu (ORCID: https://orcid.org/0009-0007-1528-974X)
- Yuanyuan Guan
- Guanjie Gao
Institutions
- Sun Yat-sen University (CN)
- Nanfang Hospital (CN)
- Vision Medicals (China) (CN)
- Third Affiliated Hospital of Sun Yat-sen University (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-10-28
- DOI
- https://doi.org/10.1186/s13287-025-04700-z
- Primary Topic
- Retinal Development and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Sun Yat-sen University
- University of Science and Technology of China
- National Key Research and Development Program of China