Single-Cell Transcriptomics Shows Cellular Heterogeneity, Intercellular Communication, and Extracellular Matrix Remodeling in Corneal Fibrosis In Vivo

This study provides an integrative transcriptomic framework of stromal cell heterogeneity, intercellular signaling, and ECM remodeling trajectories in rabbit cornea in vivo and advances mechanistic understanding of corneal repair.

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Publication Details

Journal
Investigative Ophthalmology & Visual Science
Published
2025-10-28
DOI
https://doi.org/10.1167/iovs.66.13.48
Citations
2
Primary Topic
Corneal Surgery and Treatments
Type
article
Field-Weighted Citation Impact
2.72
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article

Single-Cell Transcriptomics Shows Cellular Heterogeneity, Intercellular Communication, and Extracellular Matrix Remodeling in Corneal Fibrosis In Vivo

Nishant R. Sinha, Rajiv R. Mohan, Rajnish Kumar, Alexandria Hofmann et al.
2 citations
Investigative Ophthalmology & Visual Science
Corneal Surgery and Treatments
2.72
article

Single-Cell Transcriptomics Shows Cellular Heterogeneity, Intercellular Communication, and Extracellular Matrix Remodeling in Corneal Fibrosis In Vivo

Nishant R. Sinha, Rajiv R. Mohan, Rajnish Kumar, Alexandria Hofmann, M. Jeffrey
article en
2 citations

Abstract

This study provides an integrative transcriptomic framework of stromal cell heterogeneity, intercellular signaling, and ECM remodeling trajectories in rabbit cornea in vivo and advances mechanistic understanding of corneal repair.

Investigative Ophthalmology & Visual ScienceVol. 66(13)
Missouri College (US), Harry S. Truman Memorial Veterans' Hospital (US), University of Missouri (US)
Openalex Percentile: Top 8%
Corneal Surgery and Treatments
2.72
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