Two-Stage Hepatectomy for Cholangiocarcinoma Under Total Vascular Exclusion with Veno-venous ECMO Bypass and Controlled Closed-loop In Situ Hypothermic Oxygenated Perfusion of the Liver: The Hannover CLIP-Concept
The Hannover CLIP technique effectively combines controlled, recirculated HOPE with vvECMO. This approach minimizes ischemic injury to the liver, kidneys, and intestines and facilitates safe resection of highly complex central liver tumors under TVE.
Authors
- Philipp Felgendreff (ORCID: https://orcid.org/0000-0001-7399-8383)
- Judith Pantke
- Nora Nevermann (ORCID: https://orcid.org/0000-0003-0063-9296)
- Anna Lena Saborowski (ORCID: https://orcid.org/0000-0003-4857-4276)
- Moritz Schmelzle (ORCID: https://orcid.org/0000-0001-5400-4582)
- Markus Quante (ORCID: https://orcid.org/0000-0002-2206-107X)
- Hendrik Eismann (ORCID: https://orcid.org/0000-0003-0962-8091)
- Thomas Wirth
- C. Kühn
- Tung Yu Tsui
- Simon Störzer
- Björn Hartleben
- Cornelius J. van Beekum (ORCID: https://orcid.org/0009-0004-5864-1721)
Institutions
- Medizinische Hochschule Hannover (DE)
Publication Details
- Journal
- Annals of Surgical Oncology
- Published
- 2025-10-28
- DOI
- https://doi.org/10.1245/s10434-025-18346-x
- Citations
- 1
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.32