Genotype‐guided dual antiplatelet therapy in minor stroke or transient ischemic attack with metabolic syndrome: A post hoc analysis of <scp>CHANCE</scp> ‐2

Among CYP2C19 LOF carriers with minor stroke or TIA, patients with MetS received more clinical benefit from TIC-ASA versus CLO-ASA compared to those with non-MetS. Registry: ClinicalTrials.gov, TRN: NCT04078737.

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Publication Details

Journal
Diabetes Obesity and Metabolism
Published
2025-10-27
DOI
https://doi.org/10.1111/dom.70243
Primary Topic
Antiplatelet Therapy and Cardiovascular Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Genotype‐guided dual antiplatelet therapy in minor stroke or transient ischemic attack with metabolic syndrome: A post hoc analysis of CHANCE ‐2

Zhiyuan Feng, F Zhang, Aichun Cheng, Hao Li et al.
Diabetes Obesity and Metabolism
Antiplatelet Therapy and Cardiovascular Diseases
article

Genotype‐guided dual antiplatelet therapy in minor stroke or transient ischemic attack with metabolic syndrome: A post hoc analysis of CHANCE ‐2

Zhiyuan Feng, F Zhang, Aichun Cheng, Hao Li, Jie Xu, Aoming Jin, Jinxi Lin, Yongjun Wang, Yimeng Li, Jing Xue, Qi Chu, Xia Meng, Xinchen Li
article en

Abstract

Among CYP2C19 LOF carriers with minor stroke or TIA, patients with MetS received more clinical benefit from TIC-ASA versus CLO-ASA compared to those with non-MetS. Registry: ClinicalTrials.gov, TRN: NCT04078737.

Diabetes Obesity and MetabolismVol. 28(1)
Wannan Medical College (CN), Capital Medical University (CN), Beijing Tian Tan Hospital (CN), National Clinical Research Center for Digestive Diseases (CN), First Affiliated Hospital of Wannan Medical College (CN)
Openalex Percentile: Top 53%
Antiplatelet Therapy and Cardiovascular Diseases
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