Trends in pancreatic cancer mortality among US adults, 1999–2023

PC remains a significant and rising burden in the United States, with notable disparities by sex, age, race/ethnicity, and region. These findings highlight the importance of targeted prevention strategies, such as smoking cessation and metabolic risk control, and improving access to specialized care in non-metropolitan areas. Strengthening early detection efforts and optimizing resource allocation may help reduce these disparities and improve outcomes.