Characteristics of peripheral blood lymphocyte subsets in elderly patients with psoriasis
Elderly psoriasis patients exhibit age-related alterations in peripheral blood lymphocyte subset distribution, characterized by decreased CD8<sup>+</sup> T cells, elevated Th/Ts ratio, and increased NK cells. B cells may serve as potential biomarkers for assessing disease severity in elderly psoriasis patients.
Authors
- Ruizhen Liu
- Yehong Kuang (ORCID: https://orcid.org/0000-0002-1133-1791)
- Juan Zhao (ORCID: https://orcid.org/0000-0002-9547-887X)
- Qian Gao (ORCID: https://orcid.org/0009-0005-2412-5777)
Institutions
- Central South University (CN)
- Hunan University of Traditional Chinese Medicine (CN)
- Hunan University (CN)
- National University of Defense Technology (CN)
- Hunan Cancer Hospital (CN)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- Immunity & Ageing
- Published
- 2025-10-28
- DOI
- https://doi.org/10.1186/s12979-025-00540-w
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China