Comparative study of image quality, ADC, and IVIM data between multi-b value MUSE-DWI and SS-EPI-DWI in brain imaging

In 3.0T MRI, MUSE-DWI provided higher-quality bilateral basal ganglia images with reduced distortion. However, at b-values < 1000 s/mm², MUSE-DWI ADC values were consistently lower than SS-EPI-DWI, with discrepancy widening as b-value decreased. IVIM parameters also differed significantly. Caution is advised in interpreting ADC and IVIM data from MUSE-DWI across varying b-values. Further, larger, studies with additional analyses are required.