Differential cognitive enhancer effects of acetylcholinesterase inhibitors and memantine on age-related deficits in vigilance and sustained attention: a preclinical validation study
Here, we showed that PVT is suitable for addressing pharmacological effects on various cognitive domains in a single behavioral paradigm. Our findings also indicate that different cognitive enhancer compounds (even when their targets are thought to be the same) may differentially influence distinct cognitive domains and modulate task performance.
Authors
- Zsolt Kristóf Bali (ORCID: https://orcid.org/0000-0003-0712-0788)
- Nóra Bruszt
- István Hernádi (ORCID: https://orcid.org/0000-0001-7882-4817)
- Kitti Göntér (ORCID: https://orcid.org/0009-0006-7022-1724)
Institutions
- University of Pecs (HU)
Publication Details
- Journal
- Behavioral and Brain Functions
- Published
- 2025-10-28
- DOI
- https://doi.org/10.1186/s12993-025-00302-0
- Citations
- 1
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- Gedeon Richter
- Pécsi Tudományegyetem
- Magyarország Kormánya
- National Research, Development and Innovation Office