Mesenchymal stem cells inhibit mitochondrial fission by upregulating armadillo repeat containing 1, ameliorating oxidative stress in renal fibrosis
MSCs have the potential to improve renal fibrosis by influencing mitochondrial dynamics and oxidative stress through the upregulation of ARMC1 expression. ARMC1 may be an effective target for anti-fibrosis.
Authors
- Min Zhao (ORCID: https://orcid.org/0000-0002-1263-5965)
- Chuan Guo
- Wei Zhang (ORCID: https://orcid.org/0000-0002-5142-9769)
- Bo Chen (ORCID: https://orcid.org/0000-0003-4310-7636)
- Chang Li (ORCID: https://orcid.org/0000-0001-9588-8118)
- Tao Li (ORCID: https://orcid.org/0000-0002-6427-0830)
- Qing Liu (ORCID: https://orcid.org/0000-0003-1357-4866)
- Fei Jing (ORCID: https://orcid.org/0000-0002-2039-2684)
- Huihua Xiong
Institutions
- Southwest Medical University (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-10-28
- DOI
- https://doi.org/10.1186/s13287-025-04706-7
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Southwest Medical University