Possible shared pathogenesis between idiopathic sensory ganglionopathy and achalasia: a case report

This case underscores a possible overlapping autoimmune pathogenesis for idiopathic sensory ganglionopathy and achalasia, even in the absence of other known autoimmune disorders. The contrasting responses to immunotherapy highlight the complexity of treating coexisting conditions with distinct disease mechanisms. Further research into shared immunologic pathways may advance our understanding of these rare but notable disorders.

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Publication Details

Journal
Journal of Medical Case Reports
Published
2025-10-28
DOI
https://doi.org/10.1186/s13256-025-05635-y
Primary Topic
Gastroesophageal reflux and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Possible shared pathogenesis between idiopathic sensory ganglionopathy and achalasia: a case report

Jakkrit Amornvit, Tanisa Patcharatrakul, Punchai Pureesatien, Nath Pasuthanchat
Journal of Medical Case Reports
Gastroesophageal reflux and treatments
article

Possible shared pathogenesis between idiopathic sensory ganglionopathy and achalasia: a case report

Jakkrit Amornvit, Tanisa Patcharatrakul, Punchai Pureesatien, Nath Pasuthanchat
article en

Abstract

This case underscores a possible overlapping autoimmune pathogenesis for idiopathic sensory ganglionopathy and achalasia, even in the absence of other known autoimmune disorders. The contrasting responses to immunotherapy highlight the complexity of treating coexisting conditions with distinct disease mechanisms. Further research into shared immunologic pathways may advance our understanding of these rare but notable disorders.

Journal of Medical Case ReportsVol. 19(1)
Thai Red Cross Society (TH), Chulalongkorn University (TH), King Chulalongkorn Memorial Hospital (TH)
Openalex Percentile: Top 56%
Gastroesophageal reflux and treatments
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