Fewer Admissions, Shorter Stays: Phenobarbital Use for Alcohol Withdrawal in the Emergency Department

Phenobarbital monotherapy for AWS was associated with lower admission rates, shorter ED LOS, and fewer IV medication administrations compared to benzodiazepine-based regimens. Return visit rates were similar across all groups. These findings are exploratory, underscoring the need for prospective studies to confirm these associations.

Authors

David Cline (ORCID: https://orcid.org/0000-0002-2144-9371)
Blake Briggs (ORCID: https://orcid.org/0000-0002-5524-3291)
R. S. Green
Logan Smith (ORCID: https://orcid.org/0000-0002-3703-6870)
Noah Yates

Institutions

University of Tennessee Health Science Center (US)
University of Tennessee Medical Center (US)
Knoxville College (US)
Wake Forest University (US)
University of Tennessee at Knoxville (US)

Publication Details

Journal: Academic Emergency Medicine
Published: 2025-10-28
DOI: https://doi.org/10.1111/acem.70170
Primary Topic: Alcoholism and Thiamine Deficiency
Type: article
Field-Weighted Citation Impact: 0.00

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article

Fewer Admissions, Shorter Stays: Phenobarbital Use for Alcohol Withdrawal in the Emergency Department

David Cline, Blake Briggs, R. S. Green, Logan Smith et al.

Oct 28, 2025

Academic Emergency Medicine

Alcoholism and Thiamine Deficiency

article

Fewer Admissions, Shorter Stays: Phenobarbital Use for Alcohol Withdrawal in the Emergency Department

David Cline, Blake Briggs, R. S. Green, Logan Smith, Noah Yates

October 28, 2025article en

Abstract

Phenobarbital monotherapy for AWS was associated with lower admission rates, shorter ED LOS, and fewer IV medication administrations compared to benzodiazepine-based regimens. Return visit rates were similar across all groups. These findings are exploratory, underscoring the need for prospective studies to confirm these associations.

Academic Emergency MedicineVol. 33(2)

University of Tennessee Health Science Center (US), University of Tennessee Medical Center (US), Knoxville College (US), Wake Forest University (US), University of Tennessee at Knoxville (US)

Openalex Percentile: Top 56%

Alcoholism and Thiamine Deficiency

DOI Source OpenAlex

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Fewer Admissions, Shorter Stays: Phenobarbital Use for Alcohol Withdrawal in the Emergency Department — David Cline, Blake Briggs, et al. · Academic Emergency Medicine (2025) | TGRS Research Map | TGRS