Liraglutide upregulates the <i>Cftr</i> gene and regulates the mucus transcriptome profile in Brunner's glands in mice
Collectively, our results imply an enhanced mucus response from Brunner's glands following GLP-1R activation, which might play a role in the effect of GLP-1.
Authors
- Louise Marie Voetmann (ORCID: https://orcid.org/0000-0002-0532-3154)
- Anne Louise Bank Kodal (ORCID: https://orcid.org/0009-0008-3730-9817)
- Myrte Merkestein
- Carsten Jessen (ORCID: https://orcid.org/0000-0002-5557-2386)
- Bidda Rolin (ORCID: https://orcid.org/0000-0001-8430-3540)
- Axel Kornerup Hansen (ORCID: https://orcid.org/0000-0003-1575-2507)
- Rikke Kaae Kirk (ORCID: https://orcid.org/0000-0002-0157-9785)
- Jonas Ahnfelt‐Rønne (ORCID: https://orcid.org/0000-0002-1204-8138)
- Asli Ismihan Ozen
- Charles Pyke (ORCID: https://orcid.org/0000-0002-7286-5009)
- Lotte Bjerre Knudsen (ORCID: https://orcid.org/0000-0002-2439-7116)
Institutions
- University of Copenhagen (DK)
- Novo Nordisk (Denmark) (DK)
Publication Details
- Journal
- Clinical and Translational Medicine
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1002/ctm2.70510
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00