TREM1 deficiency attenuates LPS-induced sepsis-associated acute kidney injury by modulating macrophage polarization
These findings confirmed that TREM1 is the primary regulatory factor of macrophage plasticity in SA-AKI, proposing a therapeutic strategy for the clinical intervention of SA-AKI-related kidney diseases.
Authors
- Rong Nie (ORCID: https://orcid.org/0000-0001-8191-4581)
- Tengfang Li (ORCID: https://orcid.org/0000-0001-6345-6716)
- Longkai Peng (ORCID: https://orcid.org/0000-0002-3189-6511)
- Yanjun Zhong (ORCID: https://orcid.org/0000-0002-5057-3144)
- Xiangqi Zhang (ORCID: https://orcid.org/0000-0003-1491-3436)
- Xin Jiang (ORCID: https://orcid.org/0000-0001-9410-9215)
- Min Xu (ORCID: https://orcid.org/0000-0003-1558-4283)
- Helong Dai (ORCID: https://orcid.org/0000-0002-0696-3081)
- Ye Xu (ORCID: https://orcid.org/0009-0004-2789-4451)
- Hedong Zhang (ORCID: https://orcid.org/0000-0001-7924-5067)
- Jiangying Qin (ORCID: https://orcid.org/0000-0002-7044-8105)
- Yuxi Fan
- Qiulin Luo
- Xuefei Jin
- Jiawei Peng
- Kankan Shui
Institutions
- Union Hospital (HK)
- Central South University (CN)
- Guangxi University (CN)
- Guangxi Medical University (CN)
- Health First (US)
- Henan Provincial People's Hospital (CN)
- Second Xiangya Hospital of Central South University (CN)
- Union Hospital (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-10-28
- DOI
- https://doi.org/10.1097/js9.0000000000003836
- Primary Topic
- Inflammation biomarkers and pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00