Longitudinal Evaluation of an Abbreviated Patient‐Reported Movement Disorder Society‐sponsored revision of the Unified Parkinson's Disease Rating Scale ( <scp>MDS</scp> ‐ <scp>UPDRS)</scp> for Predicting Dopaminergic Therapy Initiation in Early Parki
Longitudinal symptom modeling improves prediction of therapy initiation in early PD. An abbreviated 11-item patient-reported MDS-UPDRS provides stronger prognostic value than the full scale and supports trial stratification and clinical monitoring. © 2025 International Parkinson and Movement Disorder Society.
Authors
- Christopher G. Goetz (ORCID: https://orcid.org/0000-0003-4457-5511)
- Tiago Mestre (ORCID: https://orcid.org/0000-0002-6973-7479)
- Glenn T. Stebbins (ORCID: https://orcid.org/0000-0001-7905-9336)
- Sheng Luo (ORCID: https://orcid.org/0000-0003-4214-5809)
- Mohammad Samsul Alam (ORCID: https://orcid.org/0000-0002-0602-5861)
- Li Yu
Institutions
- Rush University Medical Center (US)
- Duke University (US)
- Ottawa Hospital (CA)
- MIND Research Institute (US)
Publication Details
- Journal
- Movement Disorders
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1002/mds.70096
- Citations
- 1
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- International Parkinson and Movement Disorder Society
- Parkinsonfonden
- NIH Clinical Center