Pulsed Electromagnetic Field Promotes Doxorubicin-induced Apoptosis by Increasing Caspase-2 Activation in MDA-MB-231 Breast Cancer Cells

PEMF stimulation can further increase DOX-induced caspase-2 activation, which consequently potentiates Bid truncation and the subsequent activation of the intrinsic apoptotic pathway, further reducing the viability of DOX-treated MDA-MB-231 breast cancer cells.

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Publication Details

Journal
Anticancer Research
Published
2025-10-28
DOI
https://doi.org/10.21873/anticanres.17837
Primary Topic
Electromagnetic Fields and Biological Effects
Type
article
Field-Weighted Citation Impact
0.00
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article

Pulsed Electromagnetic Field Promotes Doxorubicin-induced Apoptosis by Increasing Caspase-2 Activation in MDA-MB-231 Breast Cancer Cells

Sung-Hun Woo, Yoon Suk Kim, Byung Chul Jung, Y. Lee
Anticancer Research
Electromagnetic Fields and Biological Effects
article

Pulsed Electromagnetic Field Promotes Doxorubicin-induced Apoptosis by Increasing Caspase-2 Activation in MDA-MB-231 Breast Cancer Cells

Sung-Hun Woo, Yoon Suk Kim, Byung Chul Jung, Y. Lee
article en

Abstract

PEMF stimulation can further increase DOX-induced caspase-2 activation, which consequently potentiates Bid truncation and the subsequent activation of the intrinsic apoptotic pathway, further reducing the viability of DOX-treated MDA-MB-231 breast cancer cells.

Anticancer ResearchVol. 45(11)
Korea Nazarene University (KR), Yonsei University (KR)
Openalex Percentile: Top 78%
Electromagnetic Fields and Biological Effects
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