Osteosarcoma of the Diaphysis: A Report from the Cooperative Osteosarcoma Study Group (COSS)

Diaphyseal and metaphyseal osteosarcomas share many characteristics. The former may, however, be associated with an increased rate of primary metastases and a lower response-rate to chemotherapy. Overall prognosis and prognostic factors seem comparable. Treatment strategies should follow those established for osteosarcoma.

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Publication Details

Journal
Anticancer Research
Published
2025-10-28
DOI
https://doi.org/10.21873/anticanres.17844
Primary Topic
Sarcoma Diagnosis and Treatment
Type
article
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article

Osteosarcoma of the Diaphysis: A Report from the Cooperative Osteosarcoma Study Group (COSS)

Semi Harrabi, Leo Kager, Reinhard Windhager, Wolf Hassenpflug et al.
Anticancer Research
Sarcoma Diagnosis and Treatment
article

Osteosarcoma of the Diaphysis: A Report from the Cooperative Osteosarcoma Study Group (COSS)

Semi Harrabi, Leo Kager, Reinhard Windhager, Wolf Hassenpflug, Thekla von Kalle, Jendrik Hardes, Daniel Baumhoer, Claudia Rössig, Tobias F. Feuchtinger, Claudia Blattmann, Stefan Bielack, Arndt Borkhardt, Maureen J. M. Werner, Benjamin Sorg, Godehard Friedel, Stefanie Hecker‐Nolting, Thomas Kühne, Matthias Kevric, ANTONIA KNOLL
article en

Abstract

Diaphyseal and metaphyseal osteosarcomas share many characteristics. The former may, however, be associated with an increased rate of primary metastases and a lower response-rate to chemotherapy. Overall prognosis and prognostic factors seem comparable. Treatment strategies should follow those established for osteosarcoma.

Anticancer ResearchVol. 45(11)
University of Basel (CH), Heidelberg University (DE), University Hospital Heidelberg (DE), University Hospital of Basel (CH), Ruhrlandklinik (DE), Kantonsspital Baselland (CH), Universitätsklinikum Tübingen (DE), Klinik und Poliklinik für Kinder- und Jugendmedizin (DE), University Hospital Münster (DE), Orthopädische Universitätsklinik (DE), Klinik und Poliklinik für Strahlentherapie und Radioonkologie (DE), Olgahospital (DE), St Anna Children's Hospital (AT), University Children’s Hospital Basel (CH), Universitätskinderklinik (DE), Universitätsklinik für Kinder und Jugendpsychiatrie (AT), Klinikum im Friedrichshain (DE), Klinikum Stuttgart (DE), St. Anna Children's Cancer Research Institute, Heinrich Heine University Düsseldorf (DE)
Openalex Percentile: Top 55%
Sarcoma Diagnosis and Treatment
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