Fibroblast Supernatants Modulate Treatment Responses in Human Papillomavirus Positive and Negative Oropharyngeal Cancer Cell Lines
Co-administering fibroblast BJ-hTERT cell supernatants with BYL719, JNJ-42756493, and PD-0332991 had an inhibitory effect on their effects on viability and confluence in some cell lines. This was never the case with cisplatin, and very rarely the case with docetaxel or AZD-5363.
Authors
- Madeleine Birgersson (ORCID: https://orcid.org/0000-0002-5876-0710)
- Tina Dalianis (ORCID: https://orcid.org/0000-0001-7022-2424)
- Emilia Wiecheć (ORCID: https://orcid.org/0000-0003-0270-9374)
- Ourania N. Kostopoulou
- TERÉZIA CHABANOVÁ
Institutions
- Linköping University (SE)
- Karolinska University Hospital (SE)
- Karolinska Institutet (SE)
- Industrial Development Center (Sweden) (SE)
Publication Details
- Journal
- Anticancer Research
- Published
- 2025-10-28
- DOI
- https://doi.org/10.21873/anticanres.17822
- Primary Topic
- Fibroblast Growth Factor Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Swedish Cancer Foundation
- Kommunfullmäktige, Stockholms Stad
- Karolinska Institutet