Association of Tumor Budding Grade With Immunohistochemical Expression of Thrombin and PAR-1 in Pancreatic Ductal Adenocarcinoma

The expression of thrombin in PDAC is associated with higher TB grade and could suggest a more aggressive behavior of PDAC. Both thrombin and PAR-1 represent potential targets for new anti-cancer therapeutic strategies.

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Publication Details

Journal
Anticancer Research
Published
2025-10-28
DOI
https://doi.org/10.21873/anticanres.17859
Primary Topic
Blood Coagulation and Thrombosis Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

Association of Tumor Budding Grade With Immunohistochemical Expression of Thrombin and PAR-1 in Pancreatic Ductal Adenocarcinoma

Anteja Krištić, H Loncar, Tonći Vodopić, Hrvoje Čupić et al.
Anticancer Research
Blood Coagulation and Thrombosis Mechanisms
article

Association of Tumor Budding Grade With Immunohistochemical Expression of Thrombin and PAR-1 in Pancreatic Ductal Adenocarcinoma

Anteja Krištić, H Loncar, Tonći Vodopić, Hrvoje Čupić, Ivan Franin, Monica Stephany Kirigin, Čedna Tomasović‐Lončarić, TOMISLAVA GRGURIĆ
article en

Abstract

The expression of thrombin in PDAC is associated with higher TB grade and could suggest a more aggressive behavior of PDAC. Both thrombin and PAR-1 represent potential targets for new anti-cancer therapeutic strategies.

Anticancer ResearchVol. 45(11)
University of Dubrovnik (HR), University of Zagreb (HR), University Hospital Dubrava (HR), Nova Medical (United States) (US), Sisters of Charity Hospital (HR)
Openalex Percentile: Top 61%
Blood Coagulation and Thrombosis Mechanisms
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Association of Tumor Budding Grade With Immunohistochemical Expression of Thrombin and PAR-1 in Pancreatic Ductal Adenocarcinoma — Anteja Krištić, H Loncar, et al. · Anticancer Research (2025) | TGRS Research Map | TGRS