Pathological Complete Response in Locally-advanced MSI-H/dMMR Sigmoid Colon Cancer Treated With Pembrolizumab and Abdominal Reconstruction
This case highlights the potential of pembrolizumab, in combination with aggressive surgical intervention, to achieve curative outcomes in patients with extensively invasive MSI-H/dMMR colorectal cancer.
Authors
- Taisuke Yagi
- Tomo Horinouchi
- Kota Arima
- Kozue Matsuishi
- Ryousuke Ohmura
- Yuki Kiyozumi (ORCID: https://orcid.org/0000-0003-4574-265X)
- Kenji Shimizu (ORCID: https://orcid.org/0000-0002-2732-8722)
- Katsunori Imai (ORCID: https://orcid.org/0000-0003-0549-1825)
- Kensuke Yamamura (ORCID: https://orcid.org/0000-0003-0506-6394)
- Miyako Shimasaki (ORCID: https://orcid.org/0009-0001-0900-5938)
- Kenji Sakata (ORCID: https://orcid.org/0000-0002-6312-8912)
- Toshihiko Yusa
- Masayo Tsukamoto
- Takayoshi Kaida
- Yasuo Sakamoto
- Takihiro Kamio
- Hisanobu Oda
Institutions
- Saiseikai Kumamoto Hospital (JP)
Publication Details
- Journal
- Anticancer Research
- Published
- 2025-10-28
- DOI
- https://doi.org/10.21873/anticanres.17864
- Citations
- 1
- Primary Topic
- Colorectal Cancer Surgical Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.05