Phenotypic Alteration and Suppression of Cytotoxicity of Decidual NK Cells After Co-culturing With Different Trophoblastic Cell Lines

There are certain similarities between the immune evasion of tumor cells and the physiological invasion of the trophoblastic cells of embryonic origin into the maternal decidua. Understanding the ways of interaction between dNK cells and the trophoblastic cells may reveal similar immunological interactions between the host's NK cells and tumor cells.

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Publication Details

Journal
Anticancer Research
Published
2025-10-28
DOI
https://doi.org/10.21873/anticanres.17821
Primary Topic
Immune Cell Function and Interaction
Type
article
Field-Weighted Citation Impact
0.00

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article

Phenotypic Alteration and Suppression of Cytotoxicity of Decidual NK Cells After Co-culturing With Different Trophoblastic Cell Lines

Kevin M. Elias, Thomas F. McElrath, Kathleen T Hasselblatt, Kornél Lakatos et al.
Anticancer Research
Immune Cell Function and Interaction
article

Phenotypic Alteration and Suppression of Cytotoxicity of Decidual NK Cells After Co-culturing With Different Trophoblastic Cell Lines

Kevin M. Elias, Thomas F. McElrath, Kathleen T Hasselblatt, Kornél Lakatos, Ross S. Berkowitz, Vilmos Fülöp, György Végh
article en

Abstract

There are certain similarities between the immune evasion of tumor cells and the physiological invasion of the trophoblastic cells of embryonic origin into the maternal decidua. Understanding the ways of interaction between dNK cells and the trophoblastic cells may reveal similar immunological interactions between the host's NK cells and tumor cells.

Anticancer ResearchVol. 45(11)
Brigham and Women's Hospital (US), Harvard University (US), University of Miskolc (HU), Dana-Farber Cancer Institute (US), Szent János Kórház (HU), Petz Aladár Megyei Oktató Kórház (HU), Zrínyi Miklós National Defence University (HU), Széchenyi István University (HU)
Brigham and Women's Hospital
Openalex Percentile: Top 68%
Immune Cell Function and Interaction
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Phenotypic Alteration and Suppression of Cytotoxicity of Decidual NK Cells After Co-culturing With Different Trophoblastic Cell Lines — Kevin M. Elias, Thomas F. McElrath, et al. · Anticancer Research (2025) | TGRS Research Map | TGRS