Integrated bioinformatics analysis identifies RPS27A and PPP2R1A as shared hub genes in heart failure and COVID-19
RPS27A and PPP2R1A may serve as common molecular regulators in HF and COVID-19. These findings offer potential cross-disease biomarkers and therapeutic targets for conditions driven by inflammation and immune dysregulation.
Authors
- Ling‐bing Meng (ORCID: https://orcid.org/0000-0003-1746-6109)
- Lang Tong (ORCID: https://orcid.org/0000-0003-3322-2681)
- Xinyu Liu (ORCID: https://orcid.org/0009-0003-5747-3810)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Weifang People's Hospital (CN)
- Jinhua Academy of Agricultural Sciences (CN)
- Fu Wai Hospital (CN)
- Jinhua Central Hospital (CN)
- Beihang University (CN)
Publication Details
- Journal
- Journal of Cardiothoracic Surgery
- Published
- 2025-10-28
- DOI
- https://doi.org/10.1186/s13019-025-03634-0
- Citations
- 1
- Primary Topic
- Bioinformatics and Genomic Networks
- Type
- article
- Field-Weighted Citation Impact
- 0.81