Respiratory effects of trunk inclination in obese and non-obese patients mechanically ventilated for ARDS
Increasing the trunk inclination angle during passive ventilation reduces respiratory system, lung, and chest wall compliance. This effect was more pronounced in obese patients. Moreover, only this population exhibited an increase in PaCO<sub>2</sub>. We acknowledge the methodological heterogeneity across the included studies, which may have influenced the results. Overall, our results highlight the importance of considering BMI as a significant variable that influences individual physiological responses to changes in bed inclination.
Authors
- Alejandro Bruhn (ORCID: https://orcid.org/0000-0001-8034-1937)
- Claude Guérin
- John J. Marini (ORCID: https://orcid.org/0000-0002-9851-2076)
- Guillermo Bugedo (ORCID: https://orcid.org/0000-0001-7527-6202)
- Ubbo F. Wiersema (ORCID: https://orcid.org/0000-0003-4943-5307)
- Shailesh Bihari (ORCID: https://orcid.org/0000-0001-7553-8620)
- Mehdi Mezidi (ORCID: https://orcid.org/0000-0002-8715-8323)
- John Selickman (ORCID: https://orcid.org/0000-0002-2003-9821)
- Martín H. Benites (ORCID: https://orcid.org/0000-0001-6366-534X)
- Eduardo Leite Vieira Costa (ORCID: https://orcid.org/0000-0002-6941-3626)
- Jaime Retamal (ORCID: https://orcid.org/0000-0002-6817-3659)
- Romina Battiato
- Thomas Langer (ORCID: https://orcid.org/0009-0002-4357-0487)
- Jean Dellamonica
- Francesco Marrazo
Institutions
- Université Claude Bernard Lyon 1 (FR)
- University of Minnesota (US)
- Pontificia Universidad Católica de Chile (CL)
- Universidad Nacional de Córdoba (AR)
- Flinders University (AU)
- Université Côte d'Azur (FR)
- Flinders Medical Centre (AU)
- Clínica Las Condes (CL)
- Hôpital de la Croix-Rousse (FR)
- Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda (IT)
- Hospices Civils de Lyon (FR)
- Finis Terrae University (CL)
- Observatoire de la Côte d’Azur (FR)
- Hôpital Pasteur (FR)
- Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
- Hospital Sírio-Libanês (BR)
- University of Milano-Bicocca (IT)
Publication Details
- Journal
- Critical Care
- Published
- 2025-10-28
- DOI
- https://doi.org/10.1186/s13054-025-05694-z
- Citations
- 1
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.52