Synthesis, in vitro and kinetic study of thiazolidinone derivatives: insight from a network medicinal approach for thymidine phosphorylase and alpha glucosidase
The pyridine-linked thiazolidinone analogues represent promising dual inhibitors with potential as therapeutic leads for diabetes mellitus and thymidine phosphorylase-associated disorders.
Authors
- Faez Falah Alshehri (ORCID: https://orcid.org/0000-0001-7991-0987)
- Magdi E. A. Zaki (ORCID: https://orcid.org/0000-0002-5643-9202)
- Sampath Chinnam (ORCID: https://orcid.org/0000-0002-5334-9076)
- Hamdy Kashtoh (ORCID: https://orcid.org/0000-0002-6377-1115)
- Sobhi M. Gomha (ORCID: https://orcid.org/0000-0002-7739-2837)
- Zafer Saad Al Shehri
- Eman Alzahrani
- Shoaib Khan (ORCID: https://orcid.org/0000-0001-5404-0954)
- Tayyiaba Iqbal (ORCID: https://orcid.org/0000-0003-1102-7463)
Institutions
- Taif University (SA)
- Shaqra University (SA)
- Imam Mohammad ibn Saud Islamic University (SA)
- M S Ramaiah University of Applied Sciences (IN)
- Abbottabad University of Science and Technology (PK)
- Islamic University (BD)
- Islamic University of Madinah (SA)
- Yeungnam University (KR)
Publication Details
- Journal
- Future Medicinal Chemistry
- Published
- 2025-10-28
- DOI
- https://doi.org/10.1080/17568919.2025.2571026
- Citations
- 2
- Primary Topic
- Carbohydrate Chemistry and Synthesis
- Type
- article
- Field-Weighted Citation Impact
- 1.87