Correction: Comparative analysis of cutaneous features of psoriasis in acute and chronic imiquimod-induced mouse models
Fig. 2. Effects of IMQ on the gene expression levels of pro-inflammatory mediators and epidermal markers after ST and LT treatments.Pro-inflammatory mediators (IL-17A (A), IL-1 (B), CXCL3 (C)), AMPs (BD3 (D)) and epidermal markers (KRT6 (E), KRT10 (F), IVL (G), KLK5 (H)) gene expression was assessed by RT-qPCR on total mRNAs from mouse back skin collected 24 h after the last Vaseline or IMQ application, and normalized with GAPDH (ST-Vaseline n = 25, ST-IMQ n = 32, LT-Vaseline n = 28, LT-IMQ n = 26).A Two-Way ANOVA with Bonferroni's correction was performed to compare each mediator expression after ST and LT treatments either with Vaseline or IMQ.
Authors
- Nicolas Lebonvallet (ORCID: https://orcid.org/0000-0001-7263-1408)
- Jean‐François Jégou (ORCID: https://orcid.org/0000-0002-9703-5976)
- Jean‐Claude Lecron (ORCID: https://orcid.org/0000-0003-3990-5213)
- Bérengère Fromy (ORCID: https://orcid.org/0000-0003-2457-0334)
- Hanitriniaina Rabeony (ORCID: https://orcid.org/0000-0001-6470-0514)
- Fabien Chevalier (ORCID: https://orcid.org/0000-0001-8034-8661)
- Franck Morel (ORCID: https://orcid.org/0000-0003-3812-9304)
- Emma Fraillon
- Géraldine Aimond
- Audrey Josset‐Lamaugarny
- Laurent Misery
- E. Marie-Joseph
Institutions
- Université Claude Bernard Lyon 1 (FR)
- Centre National de la Recherche Scientifique (FR)
- Université de Bretagne Occidentale (FR)
- Université de Poitiers (FR)
- Centre Hospitalier Universitaire de Poitiers (FR)
- Laboratoire des Sciences et Techniques de l’Information de la Communication et de la Connaissance (FR)
- Centre Hospitalier Régional Universitaire de Brest (FR)
- Laboratoire de Biologie Tissulaire et d'Ingénierie Thérapeutique (FR)
Publication Details
- Journal
- Scientific Reports
- Published
- 2025-10-28
- DOI
- https://doi.org/10.1038/s41598-025-25322-8
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00