Defending Irreversibility and Brain Death in the Ethics of Heart Donation After Circulatory Death

Heart donation after circulatory determination of death (DCDD) expands the donor pool but requires careful ethical grounding, particularly regarding the determination of death. This article affirms the legitimacy of brain death as a medically and ethically valid form of death, emphasizing that the irreversible cessation of brain function remains the foundational criterion. Building upon the framework proposed by Bernat and Dalle Ave, the essay promotes the concept of Donation after Brain Circulation Determination of Death (DBCDD), which ensures death is defined by the permanent cessation of brain circulation, leading inevitably to the loss of all brain function. It argues for the necessity of safeguards in DCDD protocols, including strict verification of systemic circulatory arrest and clear exclusion of cerebral reperfusion. Rather than undermining the legitimacy of DCDD, these standards uphold the integrity of brain-based death determination, reinforce the dead donor rule, and safeguard public trust. This approach unifies death determination under the brain criterion across all clinical pathways.

Authors

Institutions

Publication Details

Journal
Bioethics
Published
2025-10-27
DOI
https://doi.org/10.1111/bioe.70044
Primary Topic
Organ Donation and Transplantation
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Defending Irreversibility and Brain Death in the Ethics of Heart Donation After Circulatory Death

Calixto Machado
Bioethics
Organ Donation and Transplantation
article

Defending Irreversibility and Brain Death in the Ethics of Heart Donation After Circulatory Death

Calixto Machado
article en

Abstract

Heart donation after circulatory determination of death (DCDD) expands the donor pool but requires careful ethical grounding, particularly regarding the determination of death. This article affirms the legitimacy of brain death as a medically and ethically valid form of death, emphasizing that the irreversible cessation of brain function remains the foundational criterion. Building upon the framework proposed by Bernat and Dalle Ave, the essay promotes the concept of Donation after Brain Circulation Determination of Death (DBCDD), which ensures death is defined by the permanent cessation of brain circulation, leading inevitably to the loss of all brain function. It argues for the necessity of safeguards in DCDD protocols, including strict verification of systemic circulatory arrest and clear exclusion of cerebral reperfusion. Rather than undermining the legitimacy of DCDD, these standards uphold the integrity of brain-based death determination, reinforce the dead donor rule, and safeguard public trust. This approach unifies death determination under the brain criterion across all clinical pathways.

BioethicsVol. 40(2)
Instituto de Neurologia Y Neurocirugia (CU)
Openalex Percentile: Top 59%
Organ Donation and Transplantation
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Defending Irreversibility and Brain Death in the Ethics of Heart Donation After Circulatory Death — Calixto Machado · Bioethics (2025) | TGRS Research Map | TGRS