Interactions between multiple serum metals and genetic variants for type 2 diabetes risk: A prospective Chinese cohort study
Significant interaction effects were observed for zinc、molybdenum、barium、lead exposure and PRS. Our findings suggest that people with a high genetic risk of diabetes should pay attention to maintaining appropriate levels of metal.
Authors
- Yan Gong (ORCID: https://orcid.org/0000-0003-1329-7096)
- Zhijie Yang
- Guangfu Jin (ORCID: https://orcid.org/0000-0003-0249-5337)
- Hailan Chen (ORCID: https://orcid.org/0000-0002-5766-0531)
- Xiangxin Guo (ORCID: https://orcid.org/0000-0002-6977-3517)
- Lu Wang (ORCID: https://orcid.org/0000-0003-2525-4966)
- Jia Liu (ORCID: https://orcid.org/0000-0002-6957-3814)
- Yongchao Liu (ORCID: https://orcid.org/0000-0002-8092-9906)
- Xiaowei Zhu (ORCID: https://orcid.org/0000-0003-0041-8792)
- Qian Shen (ORCID: https://orcid.org/0000-0002-4097-6775)
- Yun Qian (ORCID: https://orcid.org/0000-0002-7921-6407)
- Man Yang (ORCID: https://orcid.org/0009-0003-2008-7959)
- Yaqi Liu (ORCID: https://orcid.org/0009-0003-8096-8889)
- Bohui Shen
Institutions
- Xian Center for Disease Control and Prevention (CN)
- Jiangsu Provincial Center for Disease Control and Prevention (CN)
- Nanjing Municipal Center for Disease Control And Prevention (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Ecotoxicology and Environmental Safety
- Published
- 2025-10-28
- DOI
- https://doi.org/10.1016/j.ecoenv.2025.119252
- Primary Topic
- Heavy Metal Exposure and Toxicity
- Type
- article
- Field-Weighted Citation Impact
- 0.00