The Plasmodium berghei merozoite protein PbGAC is critically involved in erythrocyte binding during invasion
Our findings pinpointed that PbGAC is predominantly expressed at the extreme apical region of the P. berghei merozoite and engaged in binding to the heparin-like receptors on the erythrocyte surface during merozoite invasion.
Authors
- Xiaoyu Sang (ORCID: https://orcid.org/0000-0001-8482-5146)
- Ying Feng (ORCID: https://orcid.org/0000-0003-4961-8269)
- Ning Jiang (ORCID: https://orcid.org/0000-0003-0240-2233)
- Yiwei Zhang (ORCID: https://orcid.org/0000-0003-2411-5219)
- Junying Gao (ORCID: https://orcid.org/0000-0001-9087-8789)
- Qijun Chen (ORCID: https://orcid.org/0000-0003-0356-7435)
- Ran Chen (ORCID: https://orcid.org/0000-0003-2331-0098)
Institutions
- Shenyang Medical College (CN)
- Shenyang Agricultural University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Shenyang Conservatory of Music (CN)
Publication Details
- Journal
- Parasites & Vectors
- Published
- 2025-10-28
- DOI
- https://doi.org/10.1186/s13071-025-07067-5
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00