Macrophage-derived exosomes carrying miR-30a-5p alleviates IL-13/IL4-induced epithelial-mesenchymal transition in mouse bronchial epithelial cells via Runx1
This study demonstrates that macrophage-derived EXO regulates EMT in AA. Overexpression of miR-30a-5p in macrophages can regulate the EMT of BECs by EXO pathway.
Authors
- Bin Wu (ORCID: https://orcid.org/0000-0002-8086-8568)
- Danhong Li (ORCID: https://orcid.org/0000-0001-6619-1194)
- Yu Wang (ORCID: https://orcid.org/0000-0002-9205-609X)
- Mengjie Wang (ORCID: https://orcid.org/0000-0003-3637-4787)
- Lihong Li
- Jianlin Xu (ORCID: https://orcid.org/0000-0002-4380-9067)
Institutions
- Affiliated Hospital of Hangzhou Normal University (CN)
- The First People's Hospital of Xiaoshan District, Hangzhou (CN)
Publication Details
- Journal
- BMC Pulmonary Medicine
- Published
- 2025-10-28
- DOI
- https://doi.org/10.1186/s12890-025-03960-y
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00