Effective Dose of Propranolol for Primary and Secondary Prophylaxis of Variceal Hemorrhage in Cirrhosis

Achieving ≥80 mg/day of propranolol is associated with significantly reduced VH incidence in both primary and secondary prophylaxis in patients with cirrhosis. This dose should be considered as the target dose for enhancing the effectiveness of propranolol on VH prophylaxis.

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Publication Details

Journal
Hospital Pharmacy
Published
2025-10-28
DOI
https://doi.org/10.1177/00185787251372039
Primary Topic
Liver Disease and Transplantation
Type
article
Field-Weighted Citation Impact
0.00
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article

Effective Dose of Propranolol for Primary and Secondary Prophylaxis of Variceal Hemorrhage in Cirrhosis

Maneerat Chayanupatkul, Piyameth Dilokthornsakul, Warunee Mingpun, Wilarat Saiyarat
Hospital Pharmacy
Liver Disease and Transplantation
article

Effective Dose of Propranolol for Primary and Secondary Prophylaxis of Variceal Hemorrhage in Cirrhosis

Maneerat Chayanupatkul, Piyameth Dilokthornsakul, Warunee Mingpun, Wilarat Saiyarat
article en

Abstract

Achieving ≥80 mg/day of propranolol is associated with significantly reduced VH incidence in both primary and secondary prophylaxis in patients with cirrhosis. This dose should be considered as the target dose for enhancing the effectiveness of propranolol on VH prophylaxis.

Hospital Pharmacy
Chulalongkorn University (TH), Maharaj Nakorn Chiang Mai Hospital (TH), Chiang Mai University (TH)
Openalex Percentile: Top 59%
Liver Disease and Transplantation
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